Corrigendum: Variability of the coupling of blood flow and oxygen metabolism responses in the brain: a problem for interpreting BOLD studies but potentially a new window on the underlying neural activity
نویسندگان
چکیده
AUTHOR CONTRIBUTIONS Richard B. Buxton and Amir Shmuel conceptualized the hypothesis that CBF and CMRO2 may be driven differentially by excitatory and inhibitory activity and formulated experiments to test the idea. Valerie E. M. Griffeth, Aaron B. Simon, and Farshad Moradi conducted experiments and contributed ideas on how their results could be interpreted within the hypothesis. Richard B. Buxton wrote the manuscript, and all authors contributed to editing the final version.
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Variability of the coupling of blood flow and oxygen metabolism responses in the brain: a problem for interpreting BOLD studies but potentially a new window on the underlying neural activity
Recent studies from our group and others using quantitative fMRI methods have found that variations of the coupling ratio of blood flow (CBF) and oxygen metabolism (CMRO2) responses to a stimulus have a strong effect on the BOLD response. Across a number of studies an empirical pattern is emerging in the way CBF and CMRO2 changes are coupled to neural activation: if the stimulus is modulated to...
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